AURKAIP1 Polyclonal Antibody

AURKAIP1

AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

22kDa

0.2 mg/mL

Unconjugated

WB 1:500-1:2000

Recombinant protein of human AURKAIP1

Affinity purification

28S ribosomal protein S38;AIP;AKIP;AURKA interacting protein;AURKA-interacting protein;AURKAIP 1;Aurkaip1;Aurora A kinase interacting protein;Aurora kinase A interacting protein 1;Aurora kinase A-interacting protein;FLJ20608;mitochondrial;MRP-S38

Q9NWT8