ATXN1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10990-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10990-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10990-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10990-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ATXN1
Background:
The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ATXN1
Purification method:
Affinity purification
Target Synonym:
alternative ataxin1;Ataxin-1;ATX1;ATX1;Atxn1;D6S504E;OTTHUMP00000016065;SCA1;Spinocerebellar ataxia type 1 protein
UNIProt ID:
P54253