ATP7A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-16268-20uL | 20uL | £125.00 |
Quantity:
| E-AB-16268-60uL | 60uL | £172.00 |
Quantity:
| E-AB-16268-120uL | 120uL | £237.00 |
Quantity:
| E-AB-16268-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ATP7A
Background:
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human ATP7A
Purification method:
Affinity purification
Target Synonym:
ATP 7A;ATP7A;ATP7A;ATPase copper transporting alpha polypeptide;ATPase Cu++ transporting alpha polypeptide (Menkes syndrome);ATPase Cu++ transporting alpha polypeptide;Copper pump 1;Copper transporting ATPase 1;Copper-transporting ATPase 1;Cu++ transporting P type ATPase;DSMAX;FLJ17790;MC 1;MC1;Menkes disease associated protein;Menkes disease-associated protein;Menkes syndrome;MK;MNK;OHS;OTTHUMP00000062077;SMAX3
UNIProt ID:
Q04656