ASL Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14601-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14601-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14601-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14601-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ASL
Background:
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ASL
Purification method:
Affinity purification
Target Synonym:
Argininosuccinase;Argininosuccinate lyase;Arginosuccinase;ARLY;ASAL;ASL;EC 4.3.2.1
UNIProt ID:
P04424