ASCC1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14751-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14751-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14751-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14751-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ASCC1
Background:
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:25-1:100
Immunogen:
Recombinant protein of human ASCC1
Purification method:
Affinity purification
Target Synonym:
Activating signal cointegrator 1 complex subunit 1;ASC-1 complex subunit p50;ASC1 complex subunit p50;ASC1p50;ASCC1;ASCC1;CGI 18;RP11-150D20.4;Trip4 complex subunit p50
UNIProt ID:
Q8N9N2