PYCARD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-30582-20uL | 20uL | £125.00 |
Quantity:
| E-AB-30582-60uL | 60uL | £172.00 |
Quantity:
| E-AB-30582-120uL | 120uL | £237.00 |
Quantity:
| E-AB-30582-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ASC
Background:
Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
22kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the N-terminal region of human ASC
ObservedMW:
21kDa
Purification method:
Affinity purification
Target Synonym:
Apoptosis associated speck like protein containing a CARD;Apoptosis-associated speck-like protein containing a CARD;ASC;ASC;CARD 5;CARD5;Caspase recruitment domain containing protein 5;Caspase recruitment domain protein 5;Caspase recruitment domain-containing protein 5;hASC;MGC10332;PYCARD;PYD and CARD domain containing;PYD and CARD domain containing protein;PYD and CARD domain-containing protein;Target of methylation induced silencing 1;Target of methylation-induced silencing 1;TMS 1;TMS;TMS1
UNIProt ID:
Q9ULZ3
References
- https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.23866