ARIH2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12985-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12985-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12985-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12985-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ARIH2
Background:
TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human ARIH2
Purification method:
Affinity purification
Target Synonym:
HT005;all trans retinoic acid inducible RING finger;Ari 2;Ari-2;ARI2;ARI2;Ariadne 2;Ariadne 2 protein homolog;ariadne homolog 2 (Drosophila);ariadne homolog 2;Ariadne RBR E3 ubiquitin protein ligase 2;ARIH 2;Arih2;E3 ubiquitin protein ligase ARIH2;E3 ubiquitin-protein ligase ARIH2;protein ariadne 2 homolog;Protein ariadne-2 homolog;Triad 1;TRIAD1;Triad1 protein;UIP48
UNIProt ID:
O95376