ARC Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10826-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10826-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10826-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10826-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ARC
Background:
Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ARC
Purification method:
Affinity purification
Target Synonym:
activity regulated cytoskeleton associated protein;activity regulated gene 3.1 protein homolog;Activity-regulated cytoskeleton-associated protein;Activity-regulated gene 3.1 protein homolog;Arc;ARC/ARG3.1;ARC;Arg3.1
UNIProt ID:
Q7LC44