APPL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10172-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10172-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10172-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10172-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
APPL1
Background:
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
80kDa
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300
Immunogen:
Recombinant protein of human APPL1
Purification method:
Affinity purification
Target Synonym:
Adapter protein containing PH domain;Adaptor Protein Containing pH Domain;Adaptor protein containing pH domain PTB domain and leucine zipper motif 1;Adaptor protein containing pH domain PTB domain and leucine zipper motif;Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1;AKT2 INTERACTOR;APPL 1;Appl1;DCC interacting protein 13 alpha;DCC-interacting protein 13-alpha;DIP 13 alpha;DIP13 alpha;Dip13-alpha;DIP13alpha;DP13A;KIAA1428;PTB domain and leucine zipper motif 1;PTB Domain and Leucine Zipper Motif;Signaling adaptor protein DIP13alpha
UNIProt ID:
Q9UKG1