APEX1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-10130
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-10130-20uL20uL£125.00
Quantity:
E-AB-10130-60uL60uL£172.00
Quantity:
E-AB-10130-120uL120uL£237.00
Quantity:
E-AB-10130-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Hela, 293T and A431 cell using APEX1 Polyclonal Antibody at dilution of 1:450
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Western Blot analysis of Hela, 293T and A431 cell using APEX1 Polyclonal Antibody at dilution of 1:450

Documents

Further Information

Abbreviation:
APEX1
Background:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
36kDa
Concentration:
0.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human APEX1
Purification method:
Affinity purification
Target Synonym:
AP endonuclease 1;AP endonuclease class I;AP lyase;APE 1;APE;APE-1;APEN;APEX 1;APEX;APEX nuclease (multifunctional DNA repair enzyme) 1;Apex nuclease 1;APEX nuclease;APEX1;APEX1;Apurinic endonuclease;Apurinic-apyrimidinic endonuclease 1;Apurinic/apyrimidinic (abasic) endonuclease;Apurinic/apyrimidinic endonuclease 1;Apurinic/apyrimidinic exonuclease;APX;BAP1;Deoxyribonuclease (apurinic or apyrimidinic);DNA (apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase;mitochondrial;EC 4.2.99.18;HAP 1;HAP1;Human Apurinic endonuclease 1;MGC139790;Multifunctional DNA repair enzyme;Redox factor 1;Redox factor-1;REF 1;REF 1 protein;REF-1;REF1;REF1 protein
UNIProt ID:
P27695