APEH Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12756-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12756-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12756-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12756-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
APEH
Background:
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
81kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human APEH
Purification method:
Affinity purification
Target Synonym:
AARE;ACPH;ACPH;Acyl peptide hydrolase;Acyl-peptide hydrolase;Acylamino acid releasing enzyme;Acylamino-acid-releasing enzyme;Acylaminoacyl peptidase;Acylaminoacyl-peptidase;APEH;APH;N acylaminoacyl peptide hydrolase;OPH;Oxidized protein hydrolase
UNIProt ID:
P13798