APBA2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12975-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12975-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12975-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12975-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
APBA2
Background:
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human APBA2
Purification method:
Affinity purification
Target Synonym:
Adapter protein X11beta;Amyloid beta A4 precursor protein-binding family A member 2;APBA2;APBA2;D15S1518E;HsT16821;LIN 10;MGC:14091;MGC99508;Mint 2;Mint-2;MINT2;Neuron-specific X11L protein;Neuronal Munc18-1-interacting protein 2;Phosphotyrosine binding/interacting domain (PTB) bearing protein;X11 beta;X11 like protein;X11l
UNIProt ID:
Q99767