CD13 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12771-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12771-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12771-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12771-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ANPEP
Background:
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human ANPEP
Purification method:
Affinity purification
Target Synonym:
Alanyl (membrane) aminopeptidase;Alanyl aminopeptidase;Aminopeptidase M;Aminopeptidase N;AMPN;ANPEP;AP M;AP N;AP-M;AP-N;APN;CD 13;CD13;CD13 antigen;gp150;hAPN;LAP 1;LAP1;Microsomal aminopeptidase;Myeloid plasma membrane glycoprotein CD13;p150;PEPN
UNIProt ID:
P15144