ANKMY2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14569-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14569-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14569-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14569-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ANKMY2
Background:
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
Recombinant protein of human ANKMY2
Purification method:
Affinity purification
Target Synonym:
Ankmy2;ANKY2;Ankyrin repeat and MYND domain containing 2;Ankyrin repeat and MYND domain containing protein 2;Ankyrin repeat and MYND domain-containing protein 2;DKFZP564O043;OTTHUMP00000116019;OTTHUMP00000201684;ZMYND20
UNIProt ID:
Q8IV38