APC5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10810-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10810-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10810-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10810-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ANAPC5
Background:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ANAPC5
Purification method:
Affinity purification
Target Synonym:
2510006G12Rik;AA408751;AA536819;AA986414;ANAPC 5;ANAPC5;Anaphase promoting complex subunit 5;Anaphase-promoting complex subunit 5;Apc 5;APC5;APC5;Cyclosome subunit 5;PDL 108;PDL108;Periodontal ligament fibroblast protein;RMC1
UNIProt ID:
Q9UJX4