ALOX5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10040-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10040-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10040-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10040-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ALOX5
Background:
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:150
Immunogen:
Recombinant protein of human ALOX5
Purification method:
Affinity purification
Target Synonym:
5 LO;5 LOX;5-lipoxygenase;5-LO;5-LOX;5LOX;5LPG;ALOX 5;Alox5;Arachidonate 5 lipoxygenase;Arachidonate 5-lipoxygenase;arachidonic 5-lipoxygenase alpha-10 isoform;arachidonic 5-lipoxygenase delta-10-13 isoform;arachidonic 5-lipoxygenase delta-13 isoform;arachidonic 5-lipoxygenase delta-p10 isoform;Arachidonic acid 5 lipoxygenase;Leukotriene A4 synthase;LOG 5;LOG5;LOX5;MGC163204
UNIProt ID:
P09917