ALKBH2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10700-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10700-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10700-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10700-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ALKBH2
Background:
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
29kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human ALKBH2
Purification method:
Affinity purification
Target Synonym:
2OG Fe(II) oxy DC1;9530023G02;ABH 2;ABH2;alkB alkylation repair homolog 2;ALKB2;ALKBH2 alkB;ALKBH2;Alkylated DNA repair protein alkB homolog;Alkylated DNA repair protein alkB homolog 2;Alkylation repair homolog 2;Alpha ketoglutarate dependent dioxygenase alkB homolog 2;Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2;AU016977;DNA oxidative demethylase ALKBH2;EC 1.14.11.;FLJ99103;hABH2;mABH2;MGC90512;Oxy DC1
UNIProt ID:
Q6NS38