ALKBH1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10699-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10699-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10699-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10699-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ALKBH1
Background:
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
44kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human ALKBH1
Purification method:
Affinity purification
Target Synonym:
ABH;ABH1;alkB;alkB homolog 1 histone H2A dioxygenase;AlkB;alkylation repair homolog 1 (E. coli);ALKB1;ALKBH;ALKBH1;Alkylated DNA repair protein alkB homolog 1;Alkylation repair homolog 1;Alkylation repair;alkB homolog;Alpha-ketoglutarate-dependent dioxygenase ABH1;DNA lyase ABH1;DNA oxidative demethylase ALKBH1;hABH
UNIProt ID:
Q13686