ALDH5A1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-12961-20uL | 20uL | £125.00 |
Quantity:
| E-AB-12961-60uL | 60uL | £172.00 |
Quantity:
| E-AB-12961-120uL | 120uL | £237.00 |
Quantity:
| E-AB-12961-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ALDH5A1
Background:
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human ALDH5A1
Purification method:
Affinity purification
Target Synonym:
Aldedehyde dehydrogenase 5 family;Aldehyde dehydrogenase 5 family member A1;Aldehyde dehydrogenase 5A1;Aldehyde dehydrogenase family 5 member A1;ALDH5A 1;Aldh5a1;mitochondrial;Mitochondrial succinate semialdehyde dehydrogenase;NAD(+) dependent succinic semialdehyde dehydrogenase;NAD(+)-dependent succinic semialdehyde dehydrogenase;SSADH;SSDH;SSDH;Succinate semialdehyde dehydrogenase;Succinate-semialdehyde dehydrogenase
UNIProt ID:
P51649