AKR1C1 Polyclonal Antibody

Elabscience
Product Code: E-AB-12710
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-12710-20uL20uL£125.00
Quantity:
E-AB-12710-60uL60uL£172.00
Quantity:
E-AB-12710-120uL120uL£237.00
Quantity:
E-AB-12710-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human liver cancer and breast infiltRative duct tissue, Human fetal brain tissue using AKR1C1 Polyclonal Antibody at dilution of 1:500
2 / 3
Immunohistochemistry of paraffin-embedded Human colon cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30
3 / 3
Immunohistochemistry of paraffin-embedded Human ovarian cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30

Western Blot analysis of Human liver cancer and breast infiltRative duct tissue, Human fetal brain tissue using AKR1C1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human ovarian cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30

Documents

Further Information

Abbreviation:
AKR1C1
Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
37kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Synthetic peptide of human AKR1C1
Purification method:
Affinity purification
Target Synonym:
2-dihydrobenzene-1;2-diol dehydrogenase;20 alpha (3 alpha) hydroxysteroid dehydrogenase;20 ALPHA HSD;20 alpha hydroxysteroid dehydrogenase;20-alpha-HSD;20-alpha-hydroxysteroid dehydrogenase;20ALPHAHSD;2ALPHAHSD;AK1C1;AK1C1;AKR1C1;Aldo keto reductase family 1 member C1;aldo-keto reductase C;Aldo-keto reductase family 1 member C1;Aldo-keto reductase family;1 member 1;C9;Chlordecone reductase homolog;Chlordecone reductase homolog HAKRC;DD1;DD1/DD2;DDH;DDH1;Dihydrodiol dehydrogenase 1;Dihydrodiol dehydrogenase 1/2;dihydrodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase;dihydrodiol dehydrogenase isoform DD1;Dihydrodiol dehydrogenase;type 1;H37;HAKRC;HBAB;Hepatic dihydrodiol dehydrogenase;High affinity hepatic bile acid-binding protein;High-affinity hepatic bile acid-binding protein;Indanol dehydrogenase;MBAB;MGC8954;Trans-1;Trans-1;2 dihydrobenzene 1;2 diol dehydrogenase;Type II 3 alpha hydroxysteroid dehydrogenase
UNIProt ID:
Q04828