AGXT Polyclonal Antibody

Contact us
Elabscience
Product Code: E-AB-12706
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-12706-20uL20uL£125.00
Quantity:
E-AB-12706-60uL60uL£172.00
Quantity:
E-AB-12706-120uL120uL£237.00
Quantity:
E-AB-12706-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

1 / 1
Western Blot analysis of Human fetal liver tissue and hepg2 cell using AGXT Polyclonal Antibody at dilution of 1:1050
❮❯

Western Blot analysis of Human fetal liver tissue and hepg2 cell using AGXT Polyclonal Antibody at dilution of 1:1050

Documents

Further Information

Abbreviation:
AGXT
Background:
Serine?pyruvate aminotransferase is an enzyme that in humans is encoded by the AGXT gene. This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1), also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
43kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human AGXT
Purification method:
Affinity purification
Target Synonym:
AGT;AGT1;Agxt;AGXT1;Alanine glyoxylate aminotransferase;Alanine glyoxylate aminotransferase3;Alanine--glyoxylate aminotransferase;EC 2.6.1.44;EC 2.6.1.51;Hepatic peroxisomal alanine glyoxylate aminotransferase;Hepatic peroxisomal alanine:glyoxylate aminotransferase;L alanine glyoxylate aminotransferase 1;MS773;PH1;Serine pyruvate aminotransferase;Serine--pyruvate aminotransferase;Serine--pyruvate aminotransferase;mitochondrial;Serine:pyruvate aminotransferase;SPAT;SPT;SPYA;TLH6
UNIProt ID:
P21549