AFP Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-22033-20uL | 20uL | £125.00 |
Quantity:
| E-AB-22033-60uL | 60uL | £172.00 |
Quantity:
| E-AB-22033-120uL | 120uL | £237.00 |
Quantity:
| E-AB-22033-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: Clone:2L6
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
AFP alpha 1 Fetoprotein
Background:
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Buffer:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300
Immunogen:
Synthetic Peptide
ObservedMW:
70kDa
Purification method:
Protein A purification
Target Synonym:
Afp;AFPD;Alpha fetoglobulin;Alpha fetoprotein;Alpha fetoprotein precursor;Alpha-1-fetoprotein;Alpha-fetoglobulin;Alpha-fetoprotein;alpha-fetoprotein;Hereditary persistence of;included;FETA;FETA;Hereditary persistence of alpha fetoprotein;HPAFP
UNIProt ID:
P02771