GRK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-15703-20uL | 20uL | £125.00 |
Quantity:
| E-AB-15703-60uL | 60uL | £172.00 |
Quantity:
| E-AB-15703-120uL | 120uL | £237.00 |
Quantity:
| E-AB-15703-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ADRBK1
Background:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300
Immunogen:
Synthetic peptide of human ADRBK1
Purification method:
Affinity purification
Target Synonym:
ADRBK1;Adrenergic beta receptor kinase 1;ARBK1;BARK;BARK1;Beta adrenergic receptor kinase 1;Beta ARK 1;Beta ARK1;Beta-adrenergic receptor kinase 1;Beta-ARK-1;FLJ16718;G protein coupled receptor kinase 2;G-protein coupled receptor kinase 2;GRK2
UNIProt ID:
P25098
References
- https://www.sciencedirect.com/science/article/pii/S0753332221011975