ADD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10034-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10034-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10034-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10034-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ADD1
Background:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ADD1
Purification method:
Affinity purification
Target Synonym:
ADD A;ADD1;ADDA;ADDA;Adducin 1 (alpha);Alpha adducin;Alpha-adducin;Erythrocyte adducin alpha subunit;Erythrocyte adducin subunit alpha;MGC3339;MGC44427;OTTHUMP00000151163;OTTHUMP00000151164;OTTHUMP00000151165;OTTHUMP00000218664;OTTHUMP00000218665
UNIProt ID:
P35611