ACVR2A Polyclonal Antibody

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Elabscience
Product Code: E-AB-15513
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-15513-20uL20uL£125.00
Quantity:
E-AB-15513-60uL60uL£172.00
Quantity:
E-AB-15513-120uL120uL£237.00
Quantity:
E-AB-15513-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of Human fetal brain tissue using ACVR2A Polyclonal Antibody at dilution of 1:400
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Western Blot analysis of Human fetal brain tissue using ACVR2A Polyclonal Antibody at dilution of 1:400

Documents

Further Information

Abbreviation:
ACVR2A
Background:
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Synthetic peptide of human ACVR2A
Purification method:
Affinity purification
Target Synonym:
Activin A receptor type IIA;Activin receptor type 2A;Activin receptor type IIA;Activin receptor type-2A;ACTR 2;ACTR IIA;ACTR-IIA;ACTR2;ACTRII;ACTRIIA;Acvr 2;Acvr 2A;Acvr2;ACVR2A;AVR2A;OTTHUMP00000197918
UNIProt ID:
P27037

References

  • https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.2346