ACVR2A Polyclonal Antibody
Code | Size | Price |
---|
E-AB-14487-20uL | 20uL | £125.00 |
Quantity:
E-AB-14487-60uL | 60uL | £172.00 |
Quantity:
E-AB-14487-120uL | 120uL | £237.00 |
Quantity:
E-AB-14487-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Images
Further Information
Abbreviation:
ACVR2A
Background:
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
58kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human ACVR2A
Purification method:
Affinity purification
Target Synonym:
Activin A receptor type IIA;Activin receptor type 2A;Activin receptor type IIA;Activin receptor type-2A;ACTR 2;ACTR IIA;ACTR-IIA;ACTR2;ACTRII;ACTRIIA;Acvr 2;Acvr 2A;Acvr2;ACVR2A;AVR2A;OTTHUMP00000197918
UNIProt ID:
P27037
References
- https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.2346