ACVR1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14737-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14737-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14737-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14737-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ACVR1
Background:
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human ACVR1
Purification method:
Affinity purification
Target Synonym:
Activin A receptor type I;Activin A receptor type II like kinase 2;Activin receptor type I;Activin receptor type-1;Activin receptor-like kinase 2;ACTR-I;ACTRI;Acvr1;ACVR1;ACVR1A;ACVRLK2;ALK 2;ALK-2;ALK2;FOP;Hydroxyalkyl protein kinase;Serine/threonine-protein kinase receptor R1;SKR1;TGF-B superfamily receptor type I;TGFB superfamily receptor type I;TSR-I;TSRI
UNIProt ID:
Q04771