ACTN4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14759-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14759-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14759-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14759-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ACTN4
Background:
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
105kDa
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human ACTN4
Purification method:
Affinity purification
Target Synonym:
actinin 4;Actinin alpha 4;actinin4;ACTN 4;ACTN4;ACTN4;Alpha-actinin-4;DKFZp686K23158;F actin cross linking protein;F-actin cross-linking protein;Focal segmental glomerulosclerosis 1;FSGS 1;FSGS;FSGS1;Non muscle alpha actinin 4;Non-muscle alpha-actinin 4
UNIProt ID:
O43707