ACMSD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-10712-20uL | 20uL | £125.00 |
Quantity:
| E-AB-10712-60uL | 60uL | £172.00 |
Quantity:
| E-AB-10712-120uL | 120uL | £237.00 |
Quantity:
| E-AB-10712-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
ACMSD
Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
38kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant protein of human ACMSD
Purification method:
Affinity purification
Target Synonym:
2 amino 3 carboxymuconate 6 semialdehyde decarboxylase;2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;acmsd;ACMSD;Aminocarboxymuconate semialdehyde decarboxylase;Picolinate carboxylase
UNIProt ID:
Q8TDX5