ABCG2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-30393
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-30393-20uL20uL£125.00
Quantity:
E-AB-30393-60uL60uL£172.00
Quantity:
E-AB-30393-120uL120uL£237.00
Quantity:
E-AB-30393-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
-20°C

Images

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Western Blot analysis of HT-29 cells with ABCG2 Polyclonal Antibody.
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Western Blot analysis of HT-29 cells with ABCG2 Polyclonal Antibody.

Documents

Further Information

Abbreviation:
ABCG2
Background:
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
72kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Immunogen:
Synthesized peptide derived from the Internal region of human ABCG2.
ObservedMW:
72kDa
Purification method:
Affinity purification
Target Synonym:
ABC transporter;ABC15;ABCG 2;ABCG2;ABCG2;ABCP;ATP binding cassette sub family G (WHITE) member 2;ATP binding cassette transporter G2;ATP-binding cassette sub-family G member 2;BCRP;BCRP1;BMDP;Breast cancer resistance protein;CD338;CDw338;CDw338 antigen;EST157481;GOUT1;MGC102821;Mitoxantrone resistance associated protein;Mitoxantrone resistance-associated protein;MRX;Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2;MXR;MXR1;Placenta specific ATP binding cassette transporter;Placenta specific MDR protein;Placenta-specific ATP-binding cassette transporter;UAQTL1
UNIProt ID:
Q9UNQ0

References

  • https://link.springer.com/article/10.1007/s10989-021-10212-0