AANAT Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-14757-20uL | 20uL | £125.00 |
Quantity:
| E-AB-14757-60uL | 60uL | £172.00 |
Quantity:
| E-AB-14757-120uL | 120uL | £237.00 |
Quantity:
| E-AB-14757-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
-20°C
Further Information
Abbreviation:
AANAT
Background:
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant protein of human AANAT
Purification method:
Affinity purification
Target Synonym:
AA-NAT;Aanat;Aralkylamine N-acetyltransferase;Arylalkylamine N acetyltransferase;Serotonin acetylase;Serotonin N-acetyltransferase;SNAT;SNAT
UNIProt ID:
Q16613