GTPase Kras Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40639-50uL | 50uL | £160.00 |
Quantity:
| E-AB-40639-100uL | 100uL | £230.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
KRAS
Background:
KRAS,also called p21,is a member of the Ras superfamily of proteins. It is located on human chromosome 12,and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family,the KRAS protein is a GTPase,and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies,including lung adenocarcinoma,mucinous adenoma,ductal carcinoma of the pancreas and colorectal carcinoma.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH 7.4
Calculated MW:
21 kDa
Concentration:
2.5mg/ml
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
Recombinant Human KRAS protein expressed by E.coli.
ObservedMW:
21 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
KRAS;KRAS2;RASK2;GTPase Kras;K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras;GTPase Kras
UNIProt ID:
P01116