Lgals3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40655-50uL | 50uL | £160.00 |
Quantity:
| E-AB-40655-100uL | 100uL | £230.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Lgals3
Background:
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Calculated MW:
26kDa
Concentration:
1.7mg/mL
Conjugation:
Unconjugated
Dilution:
WB:1:250-1:500
Immunogen:
Recombinant Rat Lgals3 protein expressed by E.coli
ObservedMW:
28kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; CBP 35; Galactose-specific lectin 3; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
UNIProt ID:
P08699