ATF4 Polyclonal Antibody

Elabscience
Product Code: E-AB-68245
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-68245-60uL60uL£210.00
Quantity:
E-AB-68245-120uL120uL£291.00
Quantity:
E-AB-68245-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 1
Western blot analysis of extracts of HeLa cells using ATF4 Polyclonal Antibody at 1:1000 dilution.HeLa cells were treated by tunicamycin (2 ug/mL) for 8 hours.

Western blot analysis of extracts of HeLa cells using ATF4 Polyclonal Antibody at 1:1000 dilution.HeLa cells were treated by tunicamycin (2 ug/mL) for 8 hours.

Documents

Further Information

Abbreviation:
ATF4
Background:
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
38kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ATF4
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
ATF4;CREB-2;CREB2;TAXREB67;TXREB
UNIProt ID:
P18848