(KO Validated) IGF1R Polyclonal Antibody

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Elabscience
Product Code: E-AB-68249
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-68249-60uL60uL£224.00
Quantity:
E-AB-68249-120uL120uL£317.00
Quantity:
E-AB-68249-200uL200uL£465.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts from normal (control) and IGF1R knockout (KO) 293T cells using IGF1R Polyclonal Antibody at 1:3000 dilution.
2 / 2
Western blot analysis of extracts of various cell lines using IGF1R Polyclonal Antibody at 1:3000 dilution.
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Western blot analysis of extracts from normal (control) and IGF1R knockout (KO) 293T cells using IGF1R Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using IGF1R Polyclonal Antibody at 1:3000 dilution.

Documents

Further Information

Abbreviation:
IGF1R
Background:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
154kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human IGF1R
ObservedMW:
100KDa
Purification method:
Affinity purification
Target Synonym:
IGF1R;CD221;IGFIR;IGFR;JTK13
UNIProt ID:
P08069