IGF2R Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-68294-60uL | 60uL | £210.00 |
Quantity:
| E-AB-68294-120uL | 120uL | £291.00 |
Quantity:
| E-AB-68294-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IGF2R
Background:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
274kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human IGF2R
ObservedMW:
274KDa
Purification method:
Affinity purification
Target Synonym:
IGF2R;CD222;CI-M6PR;CIMPR;M6P-R;M6P/IGF2R;MPR 300;MPR1;MPR300;MPRI
UNIProt ID:
P11717