MYH7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-68406-60uL | 60uL | £210.00 |
Quantity:
| E-AB-68406-120uL | 120uL | £291.00 |
Quantity:
| E-AB-68406-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MYH7
Background:
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
223kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human MYH7
ObservedMW:
250KDa
Purification method:
Affinity purification
Target Synonym:
MYH7;CMD1S;CMH1;MPD1;MYHCB;SPMD;SPMM;myosin-7;MYH7
UNIProt ID:
P12883