AMPKα2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90027-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90027-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90027-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
AMPKα2
Background:
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Buffer:
PBS with 0.05% proclin300,pH7.3.
Calculated MW:
62kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human PRKAA2
ObservedMW:
62kDa
Purification method:
Affinity purification
Target Synonym:
PRKAA2;AMPK;AMPK2;AMPKa2;PRKAA
UNIProt ID:
P54646