Elabscience

CHRNA2 Polyclonal Antibody

Product Code:
 
E-AB-90054
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of rat skeletal muscle using CHRNA2 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of rat skeletal muscle using CHRNA2 Polyclonal Antibody at 1:1000 dilution.

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E-AB-90054-60uL60uL£210.00
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E-AB-90054-120uL120uL£291.00
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E-AB-90054-200uL200uL£431.00
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Further Information

Abbreviation:
CHRNA2
Background:
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
58kDa/59kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CHRNA2
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
CHRNA2
UNIProt ID:
Q15822

Documents