SERCA1/ATP2A1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90070-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90070-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90070-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
SERCA1/ATP2A1
Background:
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
95kDa/109kDa/110kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human SERCA1/SERCA1/ATP2A1
ObservedMW:
110kDa
Purification method:
Affinity purification
Target Synonym:
ATP2A1;ATP2A;SERCA1
UNIProt ID:
O14983