CFHR5 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90143-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90143-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90143-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
CFHR5
Background:
This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
64kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CFHR5
ObservedMW:
75kDa
Purification method:
Affinity purification
Target Synonym:
CFHR5;CFHL5;CFHR5D;FHR-5;FHR5
UNIProt ID:
Q9BXR6