MAP4K4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90296-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90296-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90296-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
MAP4K4
Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
133kDa/138kDa/141kDa/142kDa/145kDa/150kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MAP4K4
ObservedMW:
142kDa
Purification method:
Affinity purification
Target Synonym:
MAP4K4;FLH21957;HEL-S-31;HGK;MEKKK4;NIK
UNIProt ID:
O95819