BRAT1 Polyclonal Antibody

Elabscience
Product Code: E-AB-90486
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-90486-60uL60uL£210.00
Quantity:
E-AB-90486-120uL120uL£291.00
Quantity:
E-AB-90486-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Western blot analysis of extracts of various cell lines using Brat1 Polyclonal Antibody at 1:3000 dilution.

Western blot analysis of extracts of various cell lines using Brat1 Polyclonal Antibody at 1:3000 dilution.

Documents

Further Information

Abbreviation:
BRAT1
Background:
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
30kDa/31kDa/88kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human BRAT1
ObservedMW:
95kDa
Purification method:
Affinity purification
Target Synonym:
BRAT1;BAAT1;C7orf27;RMFSL
UNIProt ID:
Q6PJG6