CASR Polyclonal Antibody
Code | Size | Price |
---|
E-AB-90546-60uL | 60uL | £210.00 |
Quantity:
E-AB-90546-120uL | 120uL | £291.00 |
Quantity:
E-AB-90546-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Images
Further Information
Abbreviation:
CASR
Background:
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
120kDa/121kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CASR
ObservedMW:
155kDa
Purification method:
Affinity purification
Target Synonym:
CASR;CAR;EIG8;FHH;FIH;GPRC2A;HHC;HHC1;HYPOC1;NSHPT;PCAR1;hCasR
UNIProt ID:
P41180