MAN1B1 Polyclonal Antibody

Elabscience
Product Code: E-AB-90672
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-90672-60uL60uL£210.00
Quantity:
E-AB-90672-120uL120uL£291.00
Quantity:
E-AB-90672-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Documents

Further Information

Abbreviation:
MAN1B1
Background:
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
79kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MAN1B1
ObservedMW:
80kDa
Purification method:
Affinity purification
Target Synonym:
MAN1B1;ERMAN1;ERManI;MANA-ER;MRT15
UNIProt ID:
Q9UKM7