AIRE Polyclonal Antibody

Elabscience
Product Code: E-AB-90748
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-90748-60uL60uL£210.00
Quantity:
E-AB-90748-120uL120uL£291.00
Quantity:
E-AB-90748-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.

Images

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Western blot analysis of extracts of various cell lines using AIRE Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using AIRE Polyclonal Antibody at 1:1000 dilution.

Documents

Further Information

Abbreviation:
AIRE
Background:
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
25kDa/35kDa/36kDa/57kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human AIRE
ObservedMW:
50kDa
Purification method:
Affinity purification
Target Synonym:
AIRE;AIRE1;APECED;APS1;APSI;PGA1
UNIProt ID:
O43918