CASR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90771-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90771-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90771-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
CASR
Background:
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
120kDa/121kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human CASR
ObservedMW:
130-260KDa
Purification method:
Affinity purification
Target Synonym:
CASR;CAR;EIG8;FHH;FIH;GPRC2A;HHC;HHC1;HYPOC1;NSHPT;PCAR1;hCasR
UNIProt ID:
P41180