ITM2B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-90962-60uL | 60uL | £210.00 |
Quantity:
| E-AB-90962-120uL | 120uL | £291.00 |
Quantity:
| E-AB-90962-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
ITM2B
Background:
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
18kDa/30kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ITM2B
ObservedMW:
30kDa
Purification method:
Affinity purification
Target Synonym:
ITM2B;ABRI;BRI;BRI2;BRICD2B;E25B;E3-16;FBD;RDGCA;imBRI2
UNIProt ID:
Q9Y287