Slit2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91130-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91130-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91130-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
Slit2
Background:
This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
168kDa/169kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000
Immunogen:
Recombinant fusion protein of human Slit2
ObservedMW:
170kDa
Purification method:
Affinity purification
Target Synonym:
SLIT2;SLIL3;Slit-2
UNIProt ID:
O94813