FIG4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-91136-60uL | 60uL | £210.00 |
Quantity:
| E-AB-91136-120uL | 120uL | £291.00 |
Quantity:
| E-AB-91136-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze/thaw cycles.
Further Information
Abbreviation:
FIG4
Background:
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
103kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000
Immunogen:
Recombinant fusion protein of human FIG4
ObservedMW:
104kDa
Purification method:
Affinity purification
Target Synonym:
FIG4;ALS11;BTOP;CMT4J;KIAA0274;SAC3;YVS;dJ249I4.1
UNIProt ID:
Q92562